Tuesday, August 1 Morning

Morning Session II: in Silico Amyloids

Chair: G.Melacini; F.Fogolari


9:00-9:05 Opening Remarks
9:05-9:30 Simulations of prion fragments oligomerization: decomposing nucleation core assemblies.

Franca Fraternali, King’s College London, UK

9:30-9:55 Insight into the self-assembly of amyloids and cross-seeding aggregation between amyloidogenic proteins

Yifat Miller, Ben-Gurion University, Israel

9:55-10:20 Modeling the aggregation of Alzheimer’s Amyloid-beta into oligomers.
Birgit Strodel, Jülich Research Centre, Germany
10:20-10:45 Molecular dynamics simulations of b2-microglobulin interaction with hydrophobic surfaces.

Federico Fogolari, University of Udine, Italy

10:45-11:15 Coffee Break
11:15-11:40 Assessing intrinsic protein disorder via computational modelling.

Mikko Karttunen, Eindhoven University of Technology, Netherlands

11:40-11:50 Nanoscale Infrared Spectroscopy: A New Emerging Tool to Investigate Proteins Misfolding and Aggregation

Francesco S. Ruggeri, U.of Cambridge, UK

11:55-12:05 Realizing being a carrier of genetic CJD and taking an active role to support research to find a solution – A personal story

Alice Anane, CJD Foundation, Israel

12:05-12:30 The role of a disordered signaling protein tail at the membrane: The Ras example

Ruth Nussinov, NCI, USA



– No afternoon session –

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